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Article
August 1952

CLEVELAND DERMATOLOGICAL SOCIETY

AMA Arch Derm Syphilol. 1952;66(2):291-297. doi:10.1001/archderm.1952.01530270141018

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Abstract

Letterer-Siwe Disease. Presented by Dr. H. H. Bremers, Dr. C. George, and Dr. C. Sunit, for Dr. R. D. Mercer.

D. N., a white boy aged 12½ months, presents a purpuric eruption of three months' duration.

He was hospitalized at Cleveland City Hospital from July 9 to 14, 1951. At that time he had a purpuric eruption over the face, on the distal extremities, and in the scalp, and there was a history of weight loss. There was a frequent dry cough, and the breath sounds were harsh. Hepatomegaly and cervical, axillary, and inguinal adenopathy were observed. A right inguinal lymph node biopsy showed moderate hyperplasia. A skin biopsy revealed chronic capillaritis and pericapillaritis. His weight was 9,200 gm.

The child was again hospitalized at Cleveland City Hospital from July 28 to Aug. 11, 1951, because of an intermittent temperature elevation to 102 F. and a cough. The rash was

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