NEVUS anemicus is a congenital malformation characterized by areas of varying size and shape which appear distinctly paler than the surrounding skin. Most frequently, there is a large pale area with irregular but sharply outlined borders surrounded by smaller satellite spots. The skin of the nevus appears normal in all respects except color and presents no abnormalities in tests for pain, heat and cold, and tactile discrimination. The surrounding skin is normal in color; also, there is no increase of pigmentation at the borders of the nevus. In the majority of cases the lesion is situated on the trunk, although the face and extremities are not exempt.
Rubbing of the nevus with a towel or ice or the application of heat makes it stand out clearly against hyperemic normal skin. If these procedures are carried on too long or too vigorously, the nevus also becomes erythematous, greatly diminish
BUTTERWORTH T, WALTERS JD. OBSERVATIONS ON THE PHARMACOLOGIC RESPONSES OF VOERNER'S NEVUS ANEMICUS. AMA Arch Derm Syphilol. 1952;66(3):333–339. doi:10.1001/archderm.1952.01530280037005
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: