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September 1952


AMA Arch Derm Syphilol. 1952;66(3):402-403. doi:10.1001/archderm.1952.01530280106021

In 1950 one of us (W. H. G.)1 called attention to the very excellent results he had obtained by the estrogen treatment of acne vulgaris in the female over a period of more than eight years. Since then both of us have continued use of estrogens systematically with the same brilliant results. At the time we first called attention to the great value of the estrogens in the treatment of acne, our findings contrasted strikingly with the opinions generally entertained by good dermatologists, although there were publications which claimed moderately good results. In the meantime the estrogens evidently have been freely tried, but it would seem, judging from personal communications received and articles published, that the results of most observers have been rather indifferent. The inconsistent results 10 years or more ago are possibly explained by the lack of proper potency in the estrogenic preparations, but this explanation would

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