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December 1952


AMA Arch Derm Syphilol. 1952;66(6):717-721. doi:10.1001/archderm.1952.01530310055008

THE ORIGINAL report of acne neonatorum was that of Kraus in 1913. He maintained that many cases previously diagnosed as sebaceous milia in infants were actually acne vulgaris. His views were supported by pathological studies, and illustrations from two cases were presented.1 The next case was that of Beatty and Bigger in 1923.2 They thought that the diagnosis was established by obtaining positive cultures for the acne bacillus and Staphylococcus aureus from the lesions. Since then, 14 additional cases have been reported. Unfortunately, many of the case reports are incomplete and therefore inadequate for full evaluation. Only a few are documented by photographs. These case reports3 are summarized in Table 1.

Certain conclusions may be drawn from Table 1. The disease favors the male sex; in 12 reported cases the patients were boys and in only 5 were they girls. Comedones were present in all cases, and