The following observation is presented as an interesting intercurrent phenomenon in a case of erythema multiforme with possible immunological significance.
H. K., a boy aged 12, was admitted to Kingston Avenue Hospital, Feb. 22, 1952, with the chief complaint of sore throat, fever, and rash of 24 hours' duration. There was no history of previous similar attacks or of rheumatic fever, allergy, or ingestion of drugs prior to onset of the present illness.
Physical examination on admission disclosed an adolescent boy, acutely ill. His temperature was 101.8 F., pulse rate 100, respiration 20 a minute and not labored. The main presenting feature was an eruption on the skin and on the mucous membranes of the eyes, nose, and mouth. The lesions on the skin were limited mainly to the extensor surfaces of the forearms, thighs, and legs. These lesions were annular in shape, with a central area of erythema surrounded