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January 1953


Author Affiliations

Jamaica, British West Indies.

AMA Arch Derm Syphilol. 1953;67(1):99-100. doi:10.1001/archderm.1953.01540010103019

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To the Editor:—I am grateful to Dr. Thulliez for his reply to correspondence on "Dermatitis and Eczema" in the September issue of the Archives.

I am glad to see that he agrees with the use of dermatitis as the general term ("a vague one") for nonspecific lesions, and eczema for the well-defined entity, although he suggests that there may be some explanation other than the "antigen-antibody" hypothesis for specific (or well-defined) lesions. We are therefore agreed on the main aspects of the plea in my letter.

It was suggested in my letter that antigen-antibody interaction determines the eczema reaction. Dr. Thulliez considers the existence of antibodies which react to particular antigens in the epidermis only a hypothesis. In support of this hypothesis I wish to quote Ratner (Ratner, B.: Allergy Anaphylaxis and Immunotherapy, Baltimore, Williams & Wilkins Company, 1943, pp. 711 and 727), who states: "The Mass

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