[Skip to Navigation]
April 1953

MYCOSIS FUNGOIDE: Diagnosis by Aspiration Technique; Observations in Skin and Bone Marrow

Author Affiliations


From the Department of Hematology, Jewish Hospital of Brooklyn.

AMA Arch Derm Syphilol. 1953;67(4):403-406. doi:10.1001/archderm.1953.01540040061009

SINCE Stroebel and Hazen in 1911 studied sections of biopsy material of skin in mycosis fungoides and described what they called typical mycosis cells as ``measuring from 8-10 microns in diameter and having an eccentric nucleus," the diagnosis of the disease has depended on the finding of these cells.1 As hematologists, we have been interested primarily in cytology, and our interest has not been confined to the study of blood cells. Starting with the aspiration of bone marrow, we have evolved a simple technique for diagnosis of various diseases, at first, by aspiration from the spleen in many hematological disorders, notably osteosclerotic anemia,2 Gaucher's disease, Hodgkin's disease, and Boeck's sarcoid,3 thence to aspiration of lymph nodes for similar hematological disorders,4 as well as for such malignant conditions as metastatic carcinoma and lymphosarcoma.5 Our search for cytological material was extended to accessible tumors

Add or change institution