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April 1953


AMA Arch Derm Syphilol. 1953;67(4):431-438. doi:10.1001/archderm.1953.01540040089014

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Chronic Benign Plaques on Mucous Membranes. Presented by Dr. Carroll F. Burgoon Jr.

L. B., a white man aged 22, presents slightly erythematous, annular, and polycyclic lesions with raised white borders located on the buccal and gingival mucous membranes. The lesions have been present continuously over a period of four years.

A blood cell count was within normal limits; roentgenograms of the chest and teeth were normal; the serologic tests for syphilis were negative, and the sedimentation rate was 27 mm. (corrected) per hour. Ear, nose, and throat consultation discovered no evidence of focal infection.

The histologic report stated that the mucosa showed an area of infiltration with acute inflammatory cells. There was a moderate degree of acanthosis and rete peg hypertrophy, and in these areas mitotic figures were not uncommon. The subjacent areas showed mononuclear cell infiltration.

Treatment by diet and with antihistaminics was ineffectual.


Dr. E. R.

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