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Article
May 1953

BENIGN INOCULATION LYMPHORETICULOSIS (CAT-SCRATCH DISEASE): Report of Two Cases with Positive Skin Tests

AMA Arch Derm Syphilol. 1953;67(5):439-442. doi:10.1001/archderm.1953.01540050003001
Abstract

SINCE the first published report of this disease under the name maladie des griffes de chat by Debré,1 reports of this disease in widely separated areas of the world indicate its widespread distribution and not infrequent occurrence. Because of the clinical manifestations, benign inoculation lymphoreticulosis may mimic other disease processes within the province of the dermatologist2 and must enter into several differential diagnoses, as is illustrated by the two cases here reported.

As described in previous reports, benign inoculation lymphoreticulosis is a self-limited disease involving a group of regional lymph nodes depending upon the site of inoculation.3 After some minor trauma to the skin, frequently but not necessarily the scratch of a cat,3 at the inoculation site a small ulcer may develop within two to four days; it may become manifest only at the time of the development of the lymphadenopathy, or it

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