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June 1953


AMA Arch Derm Syphilol. 1953;67(6):632-633. doi:10.1001/archderm.1953.01540060094016

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E. A. W., a healthy white man of 40, complained on March 11, 1952, of an itching eruption on his hands and eyelids. For about one year he had been working in a mushroom plant where mushrooms are grown commercially. The mushroom grown in this plant is the Agaricus campestris, the only mushroom of commercial importance grown in the United States. His job consisted of working the beds, picking the mushrooms and packing them in baskets. The manner in which he used his hands to pick and pack proved to be the key to the correct diagnosis, in spite of, as will be shown, a very misleading history.

Four months prior to the first examination he had picked mushrooms in a room which had been heavily and profusely dusted with an insecticide powder said to contain a nicotine compound. Four days after this exposure, blisters appeared on the pads

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