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Article
July 1953

RETICULOENDOTHELIAL CELL HYPERPLASIA IN RELATION TO ANTIMONIAL THERAPY OF MYCOSIS FUNGOIDES

Author Affiliations

NEW YORK

From the Department of Dermatology and Syphilology of the New York University Post-Graduate Medical School (Dr. Marion B. Sulzberger, Chairman), and the Skin and Cancer Unit of the New York University Hospital.

AMA Arch Derm Syphilol. 1953;68(1):1-16. doi:10.1001/archderm.1953.01540070004001
Abstract

THE PURPOSE of this investigation was to ascertain whether the response of mycosis fungoides to antimonial therapy corresponded to the degree of reticuloendothelial cell hyperplasia found on histologic examination. Eleven cases were studied. The results of the treatment of the first eight patients with antimonials have been reported.1 The case numbers of the first eight patients in the present report correspond with the order of the case numbers given in the previous publication.2 Case 9 is omitted because the patient refused further treatment due to pain following a few antimony potassium tartrate (tartar emetic) and stibophen (Fuadin) injections. Case 10 is likewise omitted because a drug eruption developed as a result of the antimony therapy and the treatment was discontinued. Three other cases not recorded in the original publication are herewith added and reported as Cases 9,3 10, and 11.

Hematoxylin and eosin stains were

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