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Article
July 1953

GRANULAR CELL MYOBLASTOMA: Report of a Case

Author Affiliations

NEW YORK; SEATTLE

From the Department of Medicine (Dermatology), New York Hospital and Cornell University Medical College.

AMA Arch Derm Syphilol. 1953;68(1):86-88. doi:10.1001/archderm.1953.01540070089014
Abstract

Striated muscle cell tumors, depending upon the type of cells from which they are derived, are classified as rhabdomyomas and myoblastomas. Rhabdomyomas are tumors derived from mature striated muscle cells, whereas myoblastomas are derived from juvenile muscle cells, or embryonic myoblasts. Abrikossoff,1 in 1926, initially described the latter tumor under the title of myoblastic myoma; it has since been referred to as myoblastoma, granular cell rhabdomyoma, and granular cell myoblastoma. Abrikossoff originally believed that the tumor cells were derived from muscle fibers undergoing changes occurring after injury. Later, he concluded that they arose from embryonal striated muscle cells. Over 200 cases have been described since the original report. Lesions are located most frequently in the upper digestive and respiratory tracts. Cutaneous lesions comprise approximately 20% of the recorded cases, being second in frequency only to lesions of the tongue. Not many of the recorded cases have been published

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