CHEMOSURGERY is a term coined by Mohs and applied to an original method for the microscopically controlled removal of cancer. Preliminary work was begun by him in 1932 after an observation that zinc chloride injected into tissues chemically killed tissues yet preserved their histologic structures. From 1932 to 1936 the procedure was used in eliminating accessible cancer in mice.1 Since 1936 Mohs has successfully used his technique in the eradication of skin cancer in humans, with results superior to those reported by any other method of destruction.2 Inasmuch as with two exceptions the cases in which there has been treatment by us have been limited to cancer of the face, a review of Mohs's cure rate in skin cancer of the face is given. In 174 cases of basal-cell cancer followed for three years 100% cure was shown. Over 30% of these were recurrent. In 94 such cases