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October 1953


Author Affiliations


From the Department of Dermatology and Syphilology, Chicago Medical School.

AMA Arch Derm Syphilol. 1953;68(4):398-401. doi:10.1001/archderm.1953.01540100038006

MULTIPLE superficial epitheliomatosis is a term describing a form of primary carcinomata of the skin.1 The disorder develops fairly early in adult life in persons exhibiting a marked tendency for multiple cutaneous neoplasms to develop. The lesions are usually limited to the trunk and face and consist of superficial scaly or crusting plaques having a very fine thread-like elevated pearly border similar to the rolled edge seen in basal-cell epithelioma. The plaques vary in size, and after many years' duration may be palm size or larger and may or may not metastasize.

Multiple epitheliomata are not infrequently seen as a manifestation in people who have had therapy with arsenicals2 or exposure to arsenicals.3 Some authors feel that arsenic is not completely exonerated even in those cases without therapeutic exposure, because occult exposure is practically universal.

Recently, I had an opportunity to observe and treat a

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