IN TWO previous papers1 we have reported our experience with Asterol dihydrochloride (2-dimethylamino-6-[beta-diethylaminoethoxy] benzothiazole) in tinea capitis due to Microsporum audouini. One of these communications1b also describes our results with this antifungal agent in cases of moniliasis and of tinea versicolor.
We have since studied the effectiveness of Asterol dihydrochloride in superficial mycological infections due to Trichophyton mentagrophytes and Trichophyton rubrum (purpureum), and our findings are herewith reported.
DERMATOMYCOSES DUE TO T. MENTAGROPHYTES
Thirty-nine patients with superficial fungus infections were studied, in all of whom T. mentagrophytes was culturally determined as the causative organism. As is shown in Table 1, listing the distribution of the areas of involvement and the results obtained, about two-thirds of these patients had infections in the acute phase and one-third in the chronic phase.
The patients with acute infections were first treated, depending on the area of involvement, with foot baths or
EDMOND EDELSON, AARON H. HASKIN, William B. Ignatoff, Edith Titsworth. ASTEROL TREATMENT OF SUPERFICIAL DERMATOMYCOSES DUE TO T. MENTAGROPHYTES AND T. PURPUREUM. AMA Arch Derm Syphilol. 1953;68(6):627–630. doi:10.1001/archderm.1953.01540120011002