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January 1954


AMA Arch Derm Syphilol. 1954;69(1):121-123. doi:10.1001/archderm.1954.01540130123018

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Keratosis Follicularis (Darier's Disease) of Bullous Type (Benign Familial Pemphigus)? Presented by Dr. Kurt Lindstrom.

Mrs. E. G. is a 27-year-old woman. At the age of 11 years, asymptomatic papules started appearing on the sides of her neck. There has been a slow increase in the number of papules and plaques ever since. The areas most prominently involved at the present time are the neck, upper trunk, palms, and soles. There are no known similar dermatoses in any of the patient's relatives. The patient also has tinea versicolor, which is clearing up with topical sodium thiosulfate.

The pathologist, Louis H. Winer, M.D., reported the microscopic examination of the biopsy specimen taken from the lesion on the central back as follows:

"Biopsy of the lesion of the back reveals a series of discrete lesions scattered along the surface of the epiderm often in relationship to the excretory ducts of sebaceous

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