DURING the eight years which have elapsed since the subject of South American blastomycosis was last discussed in a publication in English,1 numerous investigators working in the endemic areas have assembled data which necessitate extensive revision in previously held concepts of its symptomatology, pathology, mycology, and therapy. Although the occurrence of the infection seems to be limited to but a small portion of the globe, the facts known at this time concerning its pathogenesis should be easily available for study by practitioners in other regions as well, lest the search for methods of control of the medical mycoses in general be hampered by lack of awareness of some feature less elusive in this entity than in others. This communication is presented to make this information available in English.
GENERAL SURVEY
Definition.—South American blastomycosis is a progressive, usually fatal, chronic granulomatous disease of