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Calcinosis Cutis. Presented by Dr. David Omens, and (by invitation) Dr. Harold Omens and Dr. Leonard Hoit.
DISCUSSION
Dr. Theodore Cornbleet: Calcinosis is a heterogeneous group, even if we leave out of consideration the secondary variety, as that in scars and consecutive to other morbid processes. The members of the group vary as to prognosis and associated relationships. The localized variety shows surprisingly little tissue change surrounding the depots; blood calcium level is normal, and there are few or no symptoms. The disseminated variety, as shown by this woman, always involves the skin and occurs in one obviously ill. The prognosis is poor, despite little change in the blood chemistry other than an alteration in the protein fraction, usually a deficient one. The third variety is based on systemic processes such as leukemia, in which calcium is mobilized from bone and shifted and deposited elsewhere. Blood calcium, phosphorus, and phosphatase