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Article
October 1954

ERYTHEMA ANNULARE CENTRIFUGUM (DARIER'S): Clinical and Histologic Study

Author Affiliations

BALTIMORE; NORFOLK, VA.

AMA Arch Derm Syphilol. 1954;70(4):496-507. doi:10.1001/archderm.1954.01540220098012
Abstract

COLCOTT FOX,1 in 1891, under the title of erythema gyratum perstans, described an infrequent disorder of the skin of which the essential characteristic was persistent annular erythema. In 1908, Wende2 assembled several cases and published, under the title of erythema figuratum perstans, a complete and detailed account of an entity characterized by persistent erythematous lesions with annular, circinate, and gyrate forms. Between 1891 and 1916, many writers described cases under different titles of which the essentiality was persistent annular erythema similar to, if not the same as, Wende's disease.

In 1916, Darier3 described a persistent annular erythema under the title of erythema annulare centrifugum and maintained that it was a distinct entity, different from Wende's erythema figuratum perstans in that erythema annulare centrifugum was a "dry" disease, whereas Wende's erythema figuratum perstans showed evidence of vesiculation. Darier's title has become the more popular one for

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