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October 1954


AMA Arch Derm Syphilol. 1954;70(4):541-543. doi:10.1001/archderm.1954.01540220143026

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I have been using psoralens (Biomoidin solution: Bioproducts) locally to produce erythema in alopecia areata. The results have been at least as successful as with phenol followed by alcohol and have been less irritating.

Dr. Max Popper: There are a number of reports in the literature of the familial incidence of vitiligo. I recently had the opportunity to observe two sisters with this condition. The lesions in both patients occurred on identical sites. Gougerot reports a similar case in a brother and sister (Bull. Soc. franç. dermat. et syph.25:334, 1914-1915).

Vitiligo is not due to the absence of melanocytes. It has been demonstrated that the vitiliginous skin contains as many melanocytes as the normal skin (Becker, S. W., Jr.; Fitzpatrick, T. B., and Montgomery, H.: Human Melanogenesis: Cytology of Human Pigment Cells, A. M. A. Arch. Dermat. & Syph.65:511, 1952). Although the pathogenesis of vitiligo

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