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November 1954


AMA Arch Derm Syphilol. 1954;70(5):692-693. doi:10.1001/archderm.1954.01540230142020

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Lymphocytic Infiltrate of the Skin. Presented by Dr. Murray Zimmerman.

Since August, 1953, there have been recurrent reddish plaques over both zygomatic areas, which have cleared with the local use of iodine. No subjective symptoms have been present.

The physical examination revealed erythematous, slightly raised, dusky plaques which pale on pressure, over both zygomatic areas. No atrophy was present.

The histologic picture fits the description of lymphocytic infiltrate of the skin perfectly.

Quinacrine (Atabrine) treatment was started on March 23, 1954.


Dr. Murray Zimmerman (Slide): The epidermis appears normal. Just under the epidermis, a little edema and some degeneration of connective tissue are noted. There is a marked, very heavy infiltrate which is centered in the midcutis, especially around blood vessels, which are somewhat edematous. The infiltrate is composed almost entirely of small round cells which have taken a heavy stain, which I personally feel is abnormally heavy,

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