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February 1955

PACHYONYCHIA CONGENITA: A Review and New Approach to Treatment

Author Affiliations

Galveston, Texas

From the Department of Dermatology (Dr. J. Fred Mullins, Director), The University of Texas Medical Branch, Galveston.

AMA Arch Derm. 1955;71(2):265-268. doi:10.1001/archderm.1955.01540260123022

One of the most striking and distressing of the congenital dyskeratotic skin lesions is the rare and peculiar condition of pachyonychia congenita. It is distressing, not only to the patient because of the severe disability involved, but also to the physician because he faces a difficult problem in rehabilitating the persons who are unfortunate enough to have this condition. The scope of this paper includes (1) a review of the various therapeutic modalities in pachyonychia congenita, (2) the presentation of a case, and the use of hypnosis in the treatment. The selection of this method of therapy was stimulated by the report of Mason in which suggestive therapy was of great benefit in a case of congenital ichthyosiform erythroderma of Brocq.

Pachyonychia congenita is a type of dyskeratosis with lesions involving chiefly the nails and occasionally the skin and mucous membranes. Transmission is probably by a single