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February 1955


AMA Arch Derm. 1955;71(2):279-284. doi:10.1001/archderm.1955.01540260137025

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Familial Benign Chronic Pemphigus. Presented by Dr. Paul Fasal, San Rafael.

History.—This 34-year-old man first noticed his eruption 14 years ago. It has been present on his neck, umbilicus, and axillae since that time. Two sisters, three brothers, his father, and two of his father's sisters have this condition. In all cases the first lesions appeared at 20 years of age.

Examination.—When first seen by me in March, 1954, this patient presented a plaque on the right side of his neck consisting of numerous 2- to 3-mm. sized vesicles on an erythematous base. The lesions of the left axilla were less marked, and in the right axilla and umbilicus there was only moderate erythema.

Laboratory Report.—The tissue section presents the changes typical of familial benign chronic pemphigus.


Dr. Patrick Butler: I have a patient who is nicely controlled by 1 gm. of chlortetracycline (Aureomycin) daily. When

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