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April 1955

Silicon Granuloma of the Skin

Author Affiliations

Santa Rosa, Calif.

From the Division of Dermatology, Department of Medicine, Stanford University School of Medicine, San Francisco.

AMA Arch Derm. 1955;71(4):457-461. doi:10.1001/archderm.1955.01540280033006

Traumatic silicon granuloma of the skin presents a diagnostic challenge to the observer. Both clinically and histologically, it simulates the cutaneous manifestations of sarcoidosis, tuberculosis, and other granulomas. The interval of latency between siliceous implantation and appearance of lesions is usually very long, in one recorded instance 45 years.1 Therefore, a history of associated trauma is many times not obtained. The rarity of this disease has precluded extensive compilation of material by any single observer. This paper will give a brief outline of its characteristic features, based on a study of the available literature, discuss diagnostic methods and differential diagnosis, and report a new case.


In all reported cases there has been a history of trauma involving some siliceous substance, followed by normal or delayed healing of the wound. The interval of latency has varied from 2 to 45 years, with an