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Article
April 1955

INTRODUCTION OF QUINACRINE IN TREATMENT OF LUPUS ERYTHEMATOSUS

Author Affiliations

Chicago

From the Department of Dermatology, Northwestern University Medical School, and the Newberry Library.

AMA Arch Derm. 1955;71(4):520-521. doi:10.1001/archderm.1955.01540280096023
Abstract

Intellectual curiosity is a prerequisite to progress. Thus it is that advances in science, in medicine, or in technology need not necessarily be confined to favored geographic areas or only to well-endowed institutions. The curious human being may be found anywhere and may be of any race or creed. History is replete with such examples.

In 1951 Page reported the successful use of quinacrine (Mepacrine) in the therapy of lupus erythematosus.1 Page's findings were soon confirmed by many others, and quinacrine (Atabrine) has since gained wide acceptance in the treatment of lupus erythematosus in the United States as well as Europe.

However, in 1940, unbeknown to Page, Prokopchuk,2 published his observations and his method of treatment of lupus erythematosus with quinacrine (Acriquine). The Prokopchuk paper appears to be the earliest published account of the treatment of lupus erythematosus with quinacrine. As such

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