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May 1955

Intraepithelial Epithelioma (Bowen's Disease) of the Vulva

Author Affiliations

(MC), U.S.A.F.; Baltimore

From the Departments of Gynecology and Dermatology of the University of Maryland School of Medicine.

AMA Arch Derm. 1955;71(5):615-617. doi:10.1001/archderm.1955.01540290055010

The infrequency with which a diagnosis of intraepithelial epithelioma (Bowen's disease) of the vulva is made and the recent appearance of such a case at the University Hospital have prompted this case report. The first recorded instance of this condition was by Hudelo, Oury, and Cailliau1 in 1922. In 1943 Knight2 diagnosed and reported six cases of Bowen's disease of the vulva, and in his review of the literature he noted a total of 26 cases previously published. Alves de Lima and associates3 reviewed the literature subsequent to 1943 and reported eight more cases. A total of 41 cases of this condition have been recorded.


C. K., a 27-year-old white woman, was admitted to the University Hospital on Jan. 12, 1954, with a complaint of pruritus vulvae of seven years' duration. She had had the usual childhood diseases but