Dermatitis occurring during the course of drug therapy and disappearing when the offending drug has been removed has been a common clinical experience. Because of the frequency of recurrence upon resumption of therapy, such reactions are generally considered a contraindication to further use of the drug in question. For this reason many patients who otherwise have shown a favorable response to a particular medication have been deprived of its benefits. Inasmuch as dermatitis has been reported in a not inconsiderable number of patients receiving chlorpromazine,* it would be of importance to ascertain whether or not the above generalization may be applied to the use of this agent. This is the purpose of this report.
In a series of 53 patients treated for various psychiatric disorders with chlorpromazine, 7
MARGOLIS LH, BUTLER RN, FISCHER A. NONRECURRING CHLORPROMAZINE DERMATITIS. AMA Arch Derm. 1955;72(1):72–73. doi:10.1001/archderm.1955.03730310074017
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