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August 1955

ACRODERMATITIS CHRONICA ATROPHICANS: Report of a Case Treated with Chloroquine Phosphate (Aralen)

Author Affiliations

Evanston, III.

From the Department of Dermatology, Northwestern University Medical School.

AMA Arch Derm. 1955;72(2):132. doi:10.1001/archderm.1955.03730320034004

Although some cases of acrodermatitis chronica atrophicans have been benefitted by penicillin or other antibiotics, treatment for the most part has been unsatisfactory. It was gratifying, therefore, to see a typical case of this disease respond so well after treatment with chloroquine phosphate (Aralen).


E. M., a 64-year-old woman, born in Lithuania, was first seen in the outpatient clinic of Evanston Hospital on March 1, 1954, complaining of redness of her legs of one year's duration, and pruritus of the legs of two months' duration.

Examination showed the skin on the extensor aspects of the legs and forearms to be thin, dry, red, and covered with a fine scale. There were pseudosclerodermatous plaques on the lateral aspects of the lower portion of both legs. The superficial veins were prominent, owing to thinning of the skin. Laboratory studies gave normal findings with the exception

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