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Herpes Gestationis (Post Partum). Presented by Dr. E. T. Ceder, Minneapolis.
Mrs. J. R. K., aged 33, white, first experienced generalized urticarial and vesicular eruption in 1951 during fourth month of her fourth pregnancy. The dermatosis persisted during entire term of this pregnancy but was ameliorated by lotions, medicated baths, and sulfapyridine therapy. It promptly cleared on delivery of normal child. She was entirely free until November, 1954, the second month of her fifth pregnancy. Sulfapyridine therapy was instituted and was discontinued because of headaches and its ineffectiveness. Progesterone therapy, 25 mg. administered twice daily for 14 days, was without benefit. ACTH, 40 mg. daily for about 10 days, produced marked reduction in itching and activity of the process. Patient spontaneously aborted on Jan. 11, 1955, but eruption has persisted to date. Roniacol and sulfapyridine therapy have been found to be ineffective. Acthar gel, 40 units intramuscularly,