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October 1955


AMA Arch Derm. 1955;72(4):383-385. doi:10.1001/archderm.1955.03730340081016

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Lymphangiectasia. Presented by Dr. Albert A. Soifer, New Bedford, Mass.

E. A., a white, unmarried woman, received x-ray therapy in 1939 because of uterine bleeding (fibroids). Subsequently, she suffered a "nervous breakdown." In 1940, hysterectomy was performed. Six months later, she started to take mineral oil in such large quantities that the anogenital areas were constantly soaked with oil. Swelling of the vulvae appeared in 1942 and became progressively worse. Eventually swelling developed on the perineum and in the perianal area.

In 1949, the patient consulted a physician, who found on the left side of the perineum lesions which looked like "bunches of grapes." Crude podophyllum powder was prescribed for this area, but the patient used the powder on the entire anogenital area continuously for two years, in spite of a burning sensation on application.

There was diffuse erythema, edema, and induration of the anogenital area. The skin surface

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