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Granuloma Annulare, Generalized, with Possible Necrobiosis Lipoidica on Legs. Granulomatosis Disciformis Chronica Progressiva (Miescher)? Presented by Dr. George C. Andrews.
A. B., a woman aged 31, noticed an eruption on her right instep 15 years ago. New lesions developed shortly thereafter on the legs and wrists. A biopsy was made, but no definite diagnosis was made. The asymptomatic lesions persisted for 10 years and then cleared for no apparent reason, and for 3 years she had no cutaneous lesions. Now, for the past 18 months, new lesions have appeared to involve the arms, shoulders, abdomen, and legs.
The patient had scarlet fever at the age of 8 years, with no sequelae. Four years ago she developed arthritis of the ankles with swelling, from which she recovered with no sequelae. Otherwise she has been healthy. The patient's grandfather had diabetes. Her mother, father, and one sibling are living and well.
Combes FC, Machacek GF. NEW YORK DERMATOLOGICAL SOCIETY. AMA Arch Derm. 1955;72(4):385–388. doi:10.1001/archderm.1955.03730340083017
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