This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.
Urticaria Pigmentosa. Presented by Dr. Charles F. Post.
L. C., a 50-year-old white woman, was first seen three weeks ago. Three years ago she first noticed small asymptomatic "spots" on the legs, which have spread since that time. There is very slight pruritus, but numerous lesions have gradually appeared over the arms, chest, legs, and thighs. A recent thorough physical and laboratory examination by a qualified internist was negative for any physical abnormality.
Scattered over the arms, chest, legs, and thighs are numerous maculopapular 2 to 3 mm. dark reddish-blue lesions. There are no scratch marks. There is no lymphadenopathy.
Sections of skin from the "left thigh" reveal a slightly edematous epidermis, the basal layer of which varies in pigmentation. In the subepidermal cutis are numerous mononuclear cells, many of which are mast cells. Diagnosis: Urticaria pigmentosa.
DISCUSSION
Dr. C. T. Nelson: This case is remarkable for the superficial nature