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March 1956

Eccrine Spiradenoma

AMA Arch Derm. 1956;73(3):199-227. doi:10.1001/archderm.1956.01550030001001


A small painful tumor of the skin, observed relatively often in the course of examination of neoplasms contributed to the Armed Forces Institute of Pathology, has been interpreted as a benign sweat-gland adenoma. Early in our experience with these tumors it became apparent that a unique combination of specific histologic pattern and clinical character distinguished the entity.

As this series of tumors became larger and individual cases were more fully annotated, we observed certain minor variations of the pathologic structure. Comparisons of our data with reports in the literature revealed that rare histologic descriptions of this adenoma undoubtedly have appeared during the past century. Among the terms applied to the tumor by different authors were spiradenoma, hidradenoma, syringoma, hydradenoma, sweat-gland adenoma, cylindroma, and myoepithelioma.

The purpose of this report is to present the results of our clinical, statistical, and histologic investigations of