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March 1956


AMA Arch Derm. 1956;73(3):283-286. doi:10.1001/archderm.1956.01550030085020

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Pityriasis Lichenoides et Varioliformis Acuta. Presented by Dr. Louis Rubin, Rockford, Ill.

A 23-year-old white man states he had no cutaneous eruption prior to about March 1, 1955. At that time he developed a dry scaly lesion on his right thigh, and a few days later a generalized, erythematous, papular eruption. There were no premonitory symptoms.

At present on his neck, trunk, arms, upper legs, and areas of feet he has erythematous papules up to about 8 mm. in diameter. Many lesions have hemorrhagic centers and hemorrhagic crusts. Some lesions have become ulcerated, and a few have a suggestion of a vesicular center. Pruritus is marked.

Biopsy section shows the epidermis to be necrotic in one area. Bordering this there are large swollen epithelial nuclei and pale-staining binucleate cells. The cytoplasm of some epithelial cells is condensed and assumes the appearance of individual cell keratinization. Many of the

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