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April 1956

Sclerosing Lipogranuloma Resulting from Exogenous Lipids

Author Affiliations

Los Angeles

From the Veterans Administration Center, Divisions of Dermatology and Pathology, and the Departments of Medicine and Pathology, University of California Medical Center.

AMA Arch Derm. 1956;73(4):361-372. doi:10.1001/archderm.1956.01550040055008

The term ``sclerosing lipogranuloma'' has recently been proposed by Smetana and Bernhard* for a peculiar granulomatous reaction that occurs in subcutaneous fat tissue after injury of various types. It was their feeling that this traumatic sclerosing lipogranuloma is related to, but may be distinguished from, traumatic fat necrosis of the breast, relapsing nodular nonsuppurative panniculitis, adiponecrosis neonatorum, lipid pneumonia, pelvic lipogranuloma caused by iodized oils injected for uterosalpingography, and other artificial lipogranulomas. They presented 14 cases, all occurring in males. Their ages varied from 20 to 60 years. In nine cases these lesions were in the genital region, involving either the penis or the scrotum, or both. In an additional five cases the buttocks, eye, arm, and the floor of the bladder were the sites of involvement. The process had persisted in most cases for a considerable period of time, and in no instance did healing

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