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October 1956


Author Affiliations


From the Veterans Administration Research Hospital, Northwestern University Medical Center, Department of Dermatology.

AMA Arch Derm. 1956;74(4):428-429. doi:10.1001/archderm.1956.01550100096020

The lesions of leukemia cutis that are usually mentioned in the literature1 consist of macules, papules, nodules, plaques, subcutaneous tumors, petechiae, and bullae, and they are generally distributed without a definite pattern on any part of the body surface. In addition, ulcerations, both anal and oral, have been described,* but, as far as we can determine, the literature contains no record of a leukemic ulcer of the penis. We herewith report such a case, not only because of its rarity but because of its importance in differential diagnosis.

The finding in a young Negro man of an ulcer of the penis associated with regional lymphadenopathy should first suggest the diagnosis of venereal disease and particularly syphilis. Once syphilis is ruled out, there must be eliminated the remaining diseases which may produce penile ulcers: chancroid, herpes progenitalis, lymphogranuloma venereum, granuloma inguinale, epithelioma, erosive balanitis, and mycotic granulomas. At the

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