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This interesting monograph, an addition to the American Lecture Series, reviews the use of gold compounds from the year 2500 B.C. to the present. Knowledge of the chemistry metabolism, mode of action, and toxicity of gold compounds is also reviewed and considered critically.
Conclusions: mode of action—unknown; toxic reactions—unpredictable; pathogenesis and metabolic effects—not fully explained. The monograph reviews the use of gold compounds in lupus erythematosus, as well as other diseases. It is a well-written informative account, which should be of interest especially to dermatologists who practiced during the gold-therapy era of lupus erythematosus.