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November 1956


Author Affiliations


AMA Arch Derm. 1956;74(5):548-549. doi:10.1001/archderm.1956.01550110092019

It is with apprehension that one reports any new form of treatment for psoriasis. However, the results with a new form of riboflavin have been so encouraging in a limited number of cases that this preliminary report is issued.

Relatively recent discoveries on the mode of action of riboflavin have suggested its use in some of the scaly skin diseases of man. B2 deficiency in monkeys sometimes results in the appearance of a scaly dermatitis,1 and in man eruptions of this type are also associated with the B2 deficiency state, leading one to wonder whether any of the common maculo-or papulo-squamous eruptions are related to abnormalities of riboflavin metabolism.

Riboflavin is required in the oxidative process in metabolism,2 and its administration probably results in improved skin respiration.3 Most important from the point of view of this study is the necessity of this vitamin

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