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December 1956


Author Affiliations

Johnstown, Pa.

AMA Arch Derm. 1956;74(6):676. doi:10.1001/archderm.1956.01550120096021

In June, 1952, Sagher and his co-workers1 reported urticaria pigmentosa with concomitant bone changes consisting of cystic osteoporosis. Shortly thereafter, Clyman and Rein2 reported infarct-like lesions and hereditary osteochondromas associated with this disease. References to osteosclerotic changes have also appeared in the literature.3 Associated abnormalities, however, have not been limited to the osseous system. Gastrointestinal tract and reticuloendothelial disturbances and splenomegaly have also been reported.3 An increasing number of investigators, therefore, currently regard urticaria pigmentosa as a systemic disease, rather than one limited to the skin.

I recently observed a case of urticaria pigmentosa associated with a type of bone lesion hitherto unreported.

Report of a Case

A 6-week-old American boy of Slavic parentage was seen on April 18, 1955, because of a generalized slightly pruritic eruption that appeared shortly after birth. Since the onset there was a gradual extension to include most of the

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