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March 1957

Clinical Studies in Microscopy of the Skin at Moderate Magnification: Summary of Ten Years' Experience

Author Affiliations


From The Department of Dermatology of the College of Medicine of the University of Cincinnati.

AMA Arch Derm. 1957;75(3):345-360. doi:10.1001/archderm.1957.01550150029003

More than 10 years ago, I tried, unsuccessfully, to follow the wanderings of the microfilariae of Onchocerca volvulus through the superficial skin of infested persons,1 for these organisms are numerous just below the epidermis in intensive early infections. This pursuit was done with a corneal microscope, available for the study of the serious ocular manifestations of onchocerciasis, and also by means of a capillary microscope. What was more interesting was the striking picture of the surface of the skin as revealed by these microscopes. An investigative study on cutaneous microscopy was then begun and has continued to the present time.

In 1922, Jeffrey Michael2 examined the skin, as Saphier2 in 1917 and Kumer2 had done before him, with a slit-lamp microscope or dermatoscope. Kumer stated that actually since the time of Hebra surface microscopy was used in the examination of lupus. In spite