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April 1957

Warty Dyskeratoma: A Benign Cutaneous Tumor Resembling Darier's Disease Microscopically

Author Affiliations


From the Department of Dermatology and Syphilology, University of Illinois College of Medicine (Service of Marcus R. Caro, M.D.)

AMA Arch Derm. 1957;75(4):567-572. doi:10.1001/archderm.1957.01550160093012

Widespread keratosis follicularis is an entity that has been familiar to dermatologists since it was described by Darier in 1889.1 However, discrete warty lesions, usually single, with a characteristic microscopic pattern resembling keratosis follicularis have been seen from time to time by those interested in dermatopathology. Allen refers briefly to these growths as examples of "isolated Darier's disease" in his textbook.2 Montgomery mentions a lesion which appeared to be a senile keratosis of the forehead of 15 years' duration.3 Histologically it imitates the microscopic picture of keratosis follicularis. However, it was considered to be a senile keratosis exhibiting a benign type of dyskeratosis. A search throughout the dermatologic literature did not uncover a report of localized tumors resembling keratosis follicularis microscopically. I have had an opportunity to study two such lesions, clinically and microscopically. The clinical descriptions and