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April 1957


AMA Arch Derm. 1957;75(4):589-596. doi:10.1001/archderm.1957.01550160115020

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White Spongy Nevus of the Mucosa. Presented by Dr. Jacob Cohen (by invitation) Windsor, Ont., Canada.

White man, age 28. This patient and his two older brothers have had the disease since childhood. He has received treatment with injections and local therapy in the past, being considered by various practitioners to have leukoplakia.

The mucosa of the cheeks, lips, sides of the tongue, hard and soft palate, and floor of the mouth were particularly white and opalescent. The buccal mucosa was spongy in appearance, with marked thickening especially near the angles of the mouth. Slight trauma would remove much of the spongy tissue, and some patches have appeared denuded on examination. No other areas were involved.

Laboratory findings.—Cultures and direct examinations demonstrated no mycotic organisms. Biopsy Report.—The sections show unusually thick mucosal epithelium with somewhat papillomatous characteristics. The living strata are covered with thick piled-up

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