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April 1957


AMA Arch Derm. 1957;75(4):603-605. doi:10.1001/archderm.1957.01550160129024

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Acanthosis Nigricans. Presented by Dr. Kurt Lindstrom.

The patient, aged 56, had a history of a sudden onset of itching of the torso and the extremities in December, 1955, together with the simultaneous, gradual appearance of warty plaques (these were also on the torso and the extremities, but the itching was severest where the plaques were fewest.) Topical antipruritics gave little relief, but pruritis dwindled on all areas except on the back, where it gradually disappeared with x-ray therapy. History of contactants, inhalants, and internal medication yielded no etiologic information.

On Feb. 8, 1956, a barely perceptible roughening and dusky pigmentation was noted on the axillae and sides of the lower neck, whereupon an internist was consulted. The general physical condition appeared good; laboratory work and x-rays indicated no general pathology.

The pigmentation and diffuse verrucous character has become slowly more marked in the past three

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