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May 1957

Discoid Lupus Erythematosus Following Trauma: Report of Cases and Analysis of a Questionnaire

Author Affiliations

Providence, R. I.; Pawtucket, R.

From the Department of Dermatology, Boston University School of Medicine (Herbert Mescon, M.D., Professor; Dr. Kern, Instructor; Dr. Schiff, Assistant Professor).

AMA Arch Derm. 1957;75(5):685-688. doi:10.1001/archderm.1957.01550170053009

In 1924, MacLeod,1 listed the main theories concerning the etiology of lupus erythematosus as (1) local, (2) tuberculous, and (3) toxic or septic. Subsequent investigations have established the nontuberculous nature of the disease and have tended to confirm the concept of an underlying focus of infection or toxic process.

However, occasional reports of cases in which lesions developed at sites of trauma suggest that at times local factors may play a role. King-Smith,2 in 1926, reported on his series of 49 cases, 18 of which had a history of trauma prior to the appearance of lesions of lupus erythematosus. He also reviewed 30 cases which had been reported elsewhere, and 11 of them followed external trauma. During the subsequent years there have been reports in which the following types of trauma were incriminated: tattoo,3-6 friction,7 squeezing of comedones or pustules,8,9 blow from

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