[Skip to Navigation]
May 1957

Six Years' Survival in Severe Systemic Lupus Erythematosus: An Analysis of Twelve Cases

Author Affiliations


From the Department of Dermatology (E. W. Netherton, M.D., Chief), The Cleveland Clinic Foundation, and The Frank E. Bunts Educational Institute.

AMA Arch Derm. 1957;75(5):706-714. doi:10.1001/archderm.1957.01550170074013

This report is concerned with 12 patients having severe systemic lupus erythematosus (SLE). All have lived six or more years after surviving acute episodes of their illness. During the same period of observation a larger group of patients with SLE were seen who are also still living, but whose survival, in my judgment, is not remarkable since they never were very sick. It is the intent here to include only cases of those patients who were not expected to live, yet did.

It is not possible to make a statistical comparison of the systemic manifestations among this group of living patients with those in a similar number who died. Still, the study will show what now can be done for these patients. Not too many years ago this disease was considered so unstable that minor traumas, such as a tuberculin test or the simple extraction of a tooth were