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May 1957

Leiner's Disease

Author Affiliations

St. Paul, Minn.

AMA Arch Derm. 1957;75(5):729-732. doi:10.1001/archderm.1957.01550170097016

Generalized exfoliative eruptions of infancy, though observed only infrequently in America, are nevertheless of interest because of continuing confusion as to the existence and nature of Leiner's "erythrodermia desquamativa." In the experience of Leiner and other European pediatricians this disease was observed with frequency, but dermatoses of all types were then commoner, Leiner having remarked that children without some eruption were the exception. Many experienced American dermatologists have never made a diagnosis of Leiner's disease. Cole, Hodges, and Silver1 discussed the subject several years ago, and more recently Crotty,2 in Military Service, reported four instances observed in Europe but (presumably) occurring in infants born of American parents.

My interest in this disorder was activated by observance of a patient on the Pediatric Service of the University of Minnesota Hospitals.

Report of a Case*

A boy, born Nov. 1, 1955, of a diabetic

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