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May 1957


AMA Arch Derm. 1957;75(5):760-763. doi:10.1001/archderm.1957.01550170128028

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Lipoid Proteinosis (Urbach-Wiethe). Presented by Dr. Fred F. Feldman and Dr. Ben A. Newman.

A 4-year old, precocious Jewish boy, has been in good general health since birth. Hoarseness was noted in early infancy, and he was incapable of crying until he was one year old. "Eczema" of the face, neck, arms, cubital and popliteal regions was present until spontaneous disappearance at nine months of age. When he was one year old, thickening of the skin of his forehead, face, nape, and knees became apparent. It was felt by the parents that slight trauma (scratches) to the skin produced slow-healing wounds which resulted in depressed scars. Otolaryngologists have observed what appears to be "growths" and thickening of the vocal cords. Both parents feel that, in the past year, the voice has improved and that thickening of the skin has lessened. Physical examinations, blood counts, and urinalyses in an eastern city

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