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May 1957

Fundamentals of Immunology

AMA Arch Derm. 1957;75(5):786. doi:10.1001/archderm.1957.01550170154037

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This third edition of Boyd's well-known work has been completely revised and rewritten to incorporate the advances made in immunology since the last edition in 1947. The long list of bibliographic references at the end of each chapter attests to the volume of experimental data which required review. As before, there is a fairly comprehensive treatment of the nature of antigens and antibodies, their sites and mode of reaction and possible "toxic" end-products. Delayed and immediate types of hypersensitivity are treated separately, and some of the disease states in which these allergic mechanisms operate are briefly discussed. Boyd's remarks on hypersensitivity in some cutaneous reactions may not be representative of current general opinion. For example, in a tabular comparison of immediate and delayed reactions in sensitivity states, he lists urticaria and eczema as atopic disorders, characterized by circulating reagins and positive immediate skin test reactions. The histology of

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