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June 1957

Multiple Skin Necroses (Arteriolar)

Author Affiliations

Leeds, England

AMA Arch Derm. 1957;75(6):820-825. doi:10.1001/archderm.1957.01550180034009

This paper records, for the first time in this country, a case of a distinctive necrotizing skin eruption caused by occlusion of small vessels in the skin and subcutis. One of us (J. T. I.) had seen a moulage of similarly affected skin from the patient described by Dégos (1942), as well as a male patient with this disease presented by Professor Miescher in Zurich, in April, 1946.

Köhlmeier (1940, 1941) seems to have been the first to describe the disease. His patient, a man of 22, presented small necrotic lesions in the skin and died from similar lesions affecting the bowel. Köhl meier held that the causative condition was a form of thromboangiitis obliterans affecting small vessels. He was able to describe a second patient, with characteristic thromboangiitis obliterans in the legs of eight years' duration, who died with similar intestinal necroses.