Mycetoma pedis is a deep, chronic infection of the foot, characterized by sinuses, abscesses, osteitis, and hypertrophy of the tissue, resulting in deformity of the affected part. In contrast to actinomycosis, no hematogenous spread to other parts of the body takes place. On the other hand, there is no tendency to spontaneous cure, the affection resulting ultimately in invalidity. This clinical and pathological picture is quite uniform, regardless of the causative organism, of which a bewildering variety of more than 30 different species, both aerobic Actinomycetes and fungi, have been named, though only part of these were adequately described. As proposed by Chalmers and Archibald,1 the term mycetoma should be used when the condition is caused by Actinomycetes (Nocardia or Streptomyces), while maduromycosis is the term applied to infection with fungi (e. g. Madurella).
Isolation and proper identification of these micro-organisms seems today to
ZIPRKOWSKI L, ALTMANN G, DALITH F, SPITZ U. Mycetoma Pedis: Four Cases Treated with Streptomycin. AMA Arch Derm. 1957;75(6):855–863. doi:10.1001/archderm.1957.01550180069015
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: