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June 1957

Mycetoma Pedis: Four Cases Treated with Streptomycin

Author Affiliations

Tel Hashomer, Israel

From the Department of Dermatology (Dr. L. Ziprkowski), the Department of Bacteriology (G. Altmann), and from the X-Ray Department (Dr. F. Dalith), Tel Hashomer Government Hospital, Israel.

AMA Arch Derm. 1957;75(6):855-863. doi:10.1001/archderm.1957.01550180069015

Mycetoma pedis is a deep, chronic infection of the foot, characterized by sinuses, abscesses, osteitis, and hypertrophy of the tissue, resulting in deformity of the affected part. In contrast to actinomycosis, no hematogenous spread to other parts of the body takes place. On the other hand, there is no tendency to spontaneous cure, the affection resulting ultimately in invalidity. This clinical and pathological picture is quite uniform, regardless of the causative organism, of which a bewildering variety of more than 30 different species, both aerobic Actinomycetes and fungi, have been named, though only part of these were adequately described. As proposed by Chalmers and Archibald,1 the term mycetoma should be used when the condition is caused by Actinomycetes (Nocardia or Streptomyces), while maduromycosis is the term applied to infection with fungi (e. g. Madurella).

Isolation and proper identification of these micro-organisms seems today to